Advanced Preclinical Echocardiography Workshop

Training content

• Rodent LV and RV Echocardiography
• Neonate echocardiography
• Artery stiffness measurement using Vevo F2
• Microbubble contrast enhanced ultrasound
• Echo data analysis, presentation, interpretation including Strain echo imaging analysis

Session details

1.On site echocardiography (3 days)

• • Rodent echocardiography:
    1. Left Ventricular (LV) echocardiography
    2. Right Ventricular (RV) echocardiography
    3. Coronary blood flow reserve (CFR) measurement
    4. Strain imaging echocardiography
    5. Neonate mouse echocardiography
  • Microbubble contrast-enhanced ultrasound
  • Aortic arch/carotid artery stiffness measurement for aging and atherosclerosis studies

2.The following lectures will be provided by Drs. Jiwang Chen and Samuel Lee (1 day) 

• •     RV echocardiographic data analysis and presentation
  •     LV echocardiographic data analysis and presentation
  •     Artery stiffness data analysis and presentation
  •     LV strain image analysis and presentation
  •     Microbubble contrast enhanced ultrasound image analysis and presentation
  •     LV diastolic data analysis, presentation and interpretation
  •     Echocardiography in different preclinical disease models of heart failure

Why UIC?

• State-of-the-art equipment (Vevo 2100, Vevo F2)
• Renowned instructors with extensive publication records
• Real-world applications in cutting-edge cardiovascular research

SPACE IS LIMITED, 10 people each session, ACT NOW!!!

Please contact Dr. Chen to sign up and register

Jiwang Chen | chenjw@uic.edu | phone #312-355-2918

In order to register you will need a UIC iLab account. Don't have an account? Get one at:

https://rrc.uic.edu/get-started/user-registration/

Cancellation Policy: Notification must be given two weeks prior to the scheduled workshop.

Publications by the UIC Cardiovascular Research Core:

• • Zhu Z, et al. (2019). Echocardiographic Assessment of Right Ventricular Function in Experimental Models of Pulmonary Hypertension. Pulmonary Circulation. doi: 10.1177/2045894019841987.
  • Tang M, et al. (2021). Stiffness of Aortic Arch and Carotid Artery Increases in ApoE-knockout Mice with High-fat Diet: Evidence from Echocardiography. American Journal of Translational Medicine, 13(3):1352-1364.
  • Uri Galili et al. 2021. Near complete repair after myocardial infarction in adult mice by altering the inflammatory response with intramyocardial injection of α-gal nanoparticles. Frontiers in Cardiovascular Medicine  8:719160.
  • Li J, et al. (2023). Cell-penetrating PHLPP peptide improves cardiac arrest survival. J Clin Invest, 133(9).
  • Shi JY, et al. (2024). Monolithic-to-focal evolving biointerfaces in tissue regeneration and bioelectronics. Nature Chemical Engineering (in press).
  • Isbatan A and Lee S, et al. Age-Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice. Pediatric Discovery (in press).

Representative publication by our customers/collaborators:

• • Rosas PC, et al. (2023). Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension. J Vis Exp. doi: 10.3791/63775.
  • Chowdhury SAK, Rosas PC. (2022). Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice. J Vis Exp.
  • Yan G, et al. (2024). Integrated Stress Response Potentiates Ponatinib-Induced Cardiotoxicity. Circ Res. 2024 Mar;134(5):482-501. doi: 10.1161/CIRCRESAHA.123.323683.
  • Nukala SB, et al. Modulation of lncRNA links endothelial glycocalyx to vascular dysfunction of tyrosine kinase inhibitor. Cardiovasc Res. 2023 Aug 19;119(10):1997-2013. doi: 10.1093/cvr/cvad087. PMID: 37267414; PMCID: PMC10439712.

Conclusion:

This workshop offers a comprehensive, hands-on training opportunity for scientists aiming to advance their expertise in echocardiography across various animal models. Our state-of-the-art equipment, extensive publication record, and proven track record in collaboration ensure a valuable experience for all participants.